Ebola in Westafrika

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Birgitt
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Ebola-Fieber in Westafrika

Beitrag von Birgitt »

Nach Guinea, Liberia und Sierra Leone befürchtet jetzt auch Nigeria einen Ausbruch der tödlichen Seuche Ebola: Zwei möglicherweise mit dem Virus infizierte Menschen sind in dem westafrikanischen Land auf einer Krankenstation isoliert worden.
Zwei Ebola-Verdachtsfälle in Nigeria
01.08.2014 - Stern
The Ebola outbreak in West Africa is spreading faster than efforts to control it, World Health Organization (WHO) head Margaret Chan has said. She told a summit of regional leaders that failure to contain Ebola could be "catastrophic" in terms of lives lost. But she said the virus, which has claimed 728 lives in Guinea, Liberia and Sierra Leone since February, could be stopped if well managed.
Ebola crisis: Virus spreading too fast, says WHO
01.08.2014 - BBC

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Ebola - Wann gibt es einen Impfstoff ?

Beitrag von Birgitt »

Der jüngste Ausbruch des Ebola-Virus in Westafrika ist der Schlimmste bislang – nach dem Stand von Montag hat es bereits mehr als 1200 Menschen infiziert und seit dem Frühjahr mindestens 729 Opfer gefordert. Guinea, Liberia sowie Sierra Leone meldeten bestätigte Fälle, in Nigeria starb ein Infizierter, der mit dem Flugzeug aus dem Krisengebiet eingewandert war. Laut NBC News erklärte ein Funktionär von Ärzte ohne Grenzen den Ausbruch für "vollständig außer Kontrolle". Bedauerlicherweise stehen Ärzten weder wirksame Impfstoffe noch Therapien zur Verfügung. Beschäftigte in der Gesundheitsvorsorge können nichts weiteres tun als das Immunsystem der Patienten zu unterstützen, indem sie Körperflüssigkeiten, Sauerstofflevel und Blutdruck regulieren und andere Infektionen behandeln, um den Betroffenen im Kampf gegen das Virus so gut es geht zu helfen. Ein Impfstoff, der dabei hilft, zukünftige Ebola-Ausbrüche zu bekämpfen, könnte schon in ein paar Jahren greifbar sein.
Wann gibt es einen Impfstoff gegen Ebola?
01.08.2014 - spektrum

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Ebola-Fieber in Westafrika

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EBOLA VIRUS DISEASE - WEST AFRICA (111): WHO, SIERRA LEONE, VACCINE, SCREENING
******************************************************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org

In this posting:
[1] WHO update
[2] Vaccine trial
[3] Screening effectiveness
[4] Other news


******
[1] WHO update
Date: Thu 31 Jul 2014
Source: WHO Global Alert and Response, Disease Outbreak News [edited]
http://who.int/csr/don/2014_07_31_ebola/en


Ebola virus disease, West Africa -- update
------------------------------------------
Between 24-27 Jul 2014, a total of 122 new cases of Ebola virus disease (EVD; laboratory-confirmed, probable, and suspect cases) as well as 57 deaths were reported from Guinea, Liberia, Nigeria, and Sierra Leone.

[These figures and much of the text remain the same as those in previous WHO updates -- see ProMED-mail archive 20140730.2646645 and earlier. - Mod.JW]

The sample from [the Nigerian] case is yet to be sent to the WHO Collaborating Centre at the Institute Pasteur in Dakar, Senegal, due to refusal by courier companies to transport this sample. Though only one probable case has been detected so far in Nigeria, ebolavirus infection in this country represents a significant development in the course of this outbreak.

[In view of the importance of confirmation by a WHO reference lab, one would have thought that a solution would have been organized by now -- perhaps substitution of the regular courier by somebody not frightened of a triple-bagged, sanitized package? - Mod.JW]

As of 27 Jul 2014, the cumulative number of cases attributed to EVD in the 4 countries stands at 1323 including 729 deaths. The distribution and classification of the cases are as follows:
- Guinea, 460 cases (336 confirmed, 109 probable, and 15 suspected) including 339 deaths;
- Liberia, 329 cases (100 confirmed, 128 probable, and 101 suspected) including 156 deaths;
- Nigeria, 1 case (1 probable who died);
- Sierra Leone, 533 cases (473 confirmed, 38 probable, and 22 suspected) including 233 deaths.

[There is also a table showing:]
Confirmed, probable, and suspect cases and deaths from Ebola virus disease in Guinea, Liberia, and Sierra Leone, as of 27 Jul 2014 [but not Nigeria]

The total number of cases is subject to change due to reclassification, retrospective investigation, consolidation of cases and laboratory data, and enhanced surveillance. Data reported in the Disease Outbreak News are based on best available information reported by Ministries of Health.

--
Communicated by:
ProMED-mail Rapporteur Marianne Hopp

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[2] Vaccine trial
Date: Sat 2 Aug 2014
Source: Bangkok Post, AFP report [edited]
http://www.bangkokpost.com/news/world/4 ... -a-vaccine


Next month [September 2014], the US government's National Institutes of Health plan to start an early, phase I study in humans of an ebolavirus vaccine candidate that has shown promise in tests on monkeys. "We are starting to discuss some deals with pharmaceutical companies to help scale it up on an emergency basis," said Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases [NIAID]. "It might be available in 2015 for health workers who are putting themselves at extreme risk."

Some of these [candidate] vaccines have already shown 80-90 percent effectiveness in tests on monkeys, and none have had life-threatening side effects, said Cambridge University lecturer Peter Walsh. But the process has been complicated by regulators who say trying an unproven vaccine on humans would be unethical. "This argument -- that it is unethical to use non-licensed vaccines -- is just crazy," Walsh told AFP, adding that the vaccine NIAID is working on has already been a decade in the making. "The ethical thing to do is to treat them, to vaccinate them (in West Africa). It is a no-brainer. It is scandalous that we are not doing that."

Herve Raoul, a leading expert on pathogens and research director at the French Institute of Health and Medical Research (INSERM), said "A vaccine is only effective after a certain period, generally at least 3 weeks prior to exposure. The ideal thing today would be to develop an antiviral drug that would help sick people get through the most acute phase of the illness." However, there is currently no such medication in the pipeline to treat Ebola.

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[In Phase 1 trials, researchers test an experimental drug or treatment in a small group of people (20-80) for the 1st time to evaluate its safety, determine a safe dosage range, and identify side effects.

In Phase 2 trials, the experimental treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.

In Phase 3 trials, the treatment is given to large groups of people (1000-3000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow it to be used safely.

After that, these vaccinated people will have to be followed up with for months to test if they will need booster doses to maintain or improve immunity. And if some people vaccinated during an epidemic were already unknowingly infected and died soon afterwards -- or the vaccine cold chain had not been properly maintained in the field, allowing the vaccine to deteriorate -- the vaccine would be discredited, or worse, accused of causing the disease. So much could go wrong. - Mod.JW]

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[3] Screening effectiveness
Date: Fri 1 Aug 2014
Source: USA Today [edited]
http://www.usatoday.com/story/money/bus ... n/13434517


During the SARS outbreak in 2003, the WHO recommended screening passengers with questionnaires and thermal scanners, but few sick travelers were detected. Hong Kong screened 36 million passengers and detected 2 cases, and Australia screened 1.8 million people arriving, and 4 cases were detected by border screening, according to a 2005 study by K. Glass and N.G. Becker. Canada screened 4 million passengers and detected no cases, and Singapore screened 400 000 people entering the country and detected no cases, according to the study.

"The challenge for travel screening is that there is an 'incubation' period between someone being infected until they start showing symptoms," said Kathryn Glass, a fellow at Australian National University who co-authored the SARS report. "If infected people travel during that time, they are hard to spot based on symptoms. For diseases like influenza and SARS, we have the additional problem that early symptoms can be difficult to distinguish from many other conditions."

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******
[4] Other news:


US doctor walks into Atlanta hospital
-------------------------------------
2 Aug 2014: An American doctor infected with the ebolavirus in Africa was able to walk from an ambulance into an Atlanta hospital tonight after he arrived in the USA on a specially-equipped plane. It marks the 1st time anyone infected with Ebola virus disease, considered one of the world's deadliest diseases, is believed to have been brought into the country for treatment.
http://www.belfasttelegraph.co.uk/news/ ... 78770.html

[ProMED wishes Dr Brantly a speedy recovery. - Mod.JW]

WHO: health worker fatalities
-----------------------------
1 Aug 2014: Director General Margaret Chan told a summit, including the leaders of Guinea, Liberia, and Sierra Leone, that the virus was moving faster than the world's efforts to control it thus far. A striking fact is buried in her remarks:

"In addition, the outbreak is affecting a large number of doctors, nurses, and other health care workers, one of the most essential resources for containing an outbreak. To date, more than 60 health care workers have lost their lives in helping others. Some international staff are infected. These tragic infections and deaths significantly erode response capacity."

That's more than 60 dead health workers out of more than [800] dead so far -- [almost] one in 10, a jarring figure. Health workers are of course orders of magnitude more likely to contract the virus, given their close proximity to the victims. The virus, Dr. Chan carefully notes, is not transmitted by air but by contact with blood, urine, saliva, and other bodily fluids of the infected -- even after the victim has died. One would assume that many of the health workers who have succumbed did not have proper training for dealing with Ebola, and were operating under the constraints of West Africa's severely inadequate health infrastructure.
http://www.the-american-interest.com/bl ... -statistic

ICAO and World Health Organization Collaboration on Ebola Outbreak
------------------------------------------------------------------
30 Jul 2014: The International Civil Aviation Organization (ICAO), a UN specialized agency, is continuing to collaborate with representatives of the UN World Health Organization (WHO) over the Ebola virus disease (EVD) outbreak in Guinea, Liberia and Sierra Leone. Despite the increasing number of cases, the WHO recently reiterated its advice that it does not recommend any travel or trade restrictions be applied to Guinea, Liberia or Sierra Leone, based on current information. The WHO, ICAO and the International Air Transport Association (IATA) considered passenger screening revisions to the WHO document on travel and transport in light of recent events. These are still being reviewed by the WHO, which was also intending to seek inputs from the World Tourism Organization and Airports Council International (ACI).
http://www.icao.int/Newsroom/Pages/ICAO ... break.aspx

Travel advisories, USA
----------------------
1 Aug 2014: The State Department on Thursday [1 Aug 2014] issued a travel advisory warning U.S. citizens to avoid traveling to the 3 West African nations.

President Obama addressed Ebola in a press conference Friday [1 Aug 2014]. "I know it's on people's minds," he said, after highlighting the strategic and economic issues he hoped to tackle at the [forthcoming] summit [of African leaders to be held 4-6 Aug in Washington DC, USA].
http://www.usatoday.com/story/news/nati ... /13487699/

[But ProMED-mail Rapporteur Kunihiko Iizuka couldn't find such an advisory on the site of US DOS, and neither could I. http://travel.state.gov/content/passpor ... nings.html. CDC has, however, elevated its Travel Warnings to Level 3, Avoid Nonessential Travel (the top level) for all 3 countries (not including Nigeria). - Mod.JW]

Missionaries evacuated
----------------------
1 Aug 2014: The LDS Church [Church of Jesus Christ of Latter-day Saints, aka Mormon Church] is transferring all of its 274 missionaries out of Sierra Leone and Liberia, where the deadliest-known Ebola virus disease outbreak in history has killed hundreds of people, including 2 Mormons. The church announced the decision Friday [1 Aug 2014]. "We are aware of 2 members who have died from the ebolavirus," church spokeswoman Jessica Moody said, apparently one in Sierra Leone and one in Liberia.
http://www.deseretnews.com/article/8656 ... tml?pg=all

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[There is an excellent map of the current situation at: http://www.usatoday.com/story/news/nati ... /13487699/ (scroll down to see). - Mod.JW]
Götz Krieger
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Re: Ebola - Guinea, Liberia, Sierra Leone und Nigeria

Beitrag von Götz Krieger »

US-Seuchenexperte: "Wir wissen, wie wir Ebola stoppen können"

Mehr als 700 Menschen sind in Afrika an Ebola gestorben. US-Experten sagen, der Ausbruch sei außer Kontrolle. Dennoch sind sie optimistisch, dass sich die Verbreitung des Virus bald eindämmen lässt.

Washington - Die US-Seuchenschutzbehörde CDC hat sich zuversichtlich im Kampf gegen die Ebola-Epidemie gezeigt. Der Ausbruch sei zwar außer Kontrolle, sagte CDC-Direktor Tom Frieden am Sonntag im US-Fernsehsender ABC. Aber: "Wir wissen, wie wir Ebola stoppen können." Die zum Einsatz kommenden Methoden seien bereits erprobt. Man müsse die Erkrankten unter Quarantäne stellen und behandeln und das Virus an der Quelle stoppen. Frieden kündigte an, dass 50 US-Experten binnen der kommenden 30 Tage nach Westafrika entsendet werden.

Am Wochenende war der mit Ebola infizierte US-Arzt Kent Brantly in den Bundesstaat Georgia geflogen worden. Er wird in der Universitätsklinik Emory in Atlanta behandelt, dort befindet sich eine von vier Isolierstationen in den USA, die auf die Behandlung von Patienten mit höchst gefährlichen Infektionen eingestellt ist. Brantly gehe es schon etwas besser, sagte CDC-Direktor Frieden....
http://www.spiegel.de/gesundheit/diagno ... 84318.html

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Ebola in Westafrika

Beitrag von Birgitt »

EBOLA VIRUS DISEASE - WEST AFRICA (112): WHO, USA CASE REPATRIATED, MORE
************************************************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org

In this update:
[1] WHO update
[2] USA: no need to panic
[3] Other news
[4] WHO Case definition recommendations for EVD


******
[1] WHO update
Date: 3 Aug 2014
Source: WHO/AFRO [edited]
http://www.afro.who.int/en/clusters-a-p ... -2014.html


As of 30 Jul 2014, the cumulative number of cases attributed to EVD in the 4 countries stands at 1440 including 826 deaths. The distribution and classification of the cases are as follows:

- Guinea, 472 cases (337 confirmed, 122 probable, and 12 suspected) including 346 deaths;
- Liberia, 391 cases (109 confirmed, 181 probable, and 101 suspected) including 227 deaths;
- Sierra Leone, 574 cases (507 confirmed, 41 probable, and 26 suspected) including 252 deaths;
- Nigeria, 3 cases (1 probable and 2 suspected) and 1 death.

[See [4] below for WHO definitions of confirmed, probable & suspected for EVD. - Mod.JW]

Between 28-30 Jul 2014, 55 new cases (laboratory-confirmed, probable, and suspect cases) of EVD, and 58 deaths, were reported from the 4 countries as follows:

- Guinea, 5 new cases [including] 3 deaths;
- Liberia, 31 new cases [including] 46 deaths;
- Sierra Leone, 17 new cases [including] 9 deaths;
- Nigeria, 2 new suspected cases which on 1st test were negative.

The surge in the number of new EVD cases, especially in Liberia and Sierra Leone, calls for concentrated efforts by all to address the identified problems such as health facility transmission and effective contact tracing. More human resources experts are requested in these 2 countries to really tackle the progress of this outbreak. The situation in Guinea seems to be stable these 2 last days.

In Nigeria, 2 suspected cases among the contacts followed up at the airport were tested negative in the 1st PCR test. Another test will be done 48 hours later to confirm the status. The contact tracing is continuing as well as communication activities.

In Togo, some passengers from the flight to Lagos disembarked in Lome, and our epidemiologists in the field are working with the services at the airport to find out their addresses for contact tracing. The Togo and Nigeria EVD operational plans have been finalized and sent. The national authorities in Nigeria, Togo and Ghana continue to work closely with WHO and partners in identification of contacts and contact tracing as well as in preparing response plans [This suggests that, as he had no symptoms on embarkation in Sierra Leone, he developed them some time between Accra, Ghana & Lome, Togo. There is a table of confirmed, probable, and suspect cases and deaths from Ebola virus disease in Guinea, Liberia, Sierra Leone and Nigeria as of 30 Jul 2014 in the source. - Mod.JW].

The total number of cases is subject to change due to ongoing reclassification, retrospective investigation and availability of laboratory results. Data reported in the Disease Outbreak News are based on official information reported by Ministries of Health.

WHO does not recommend any travel or trade restrictions be applied to Guinea, Liberia, Sierra Leone or Nigeria based on the current information available for this event [Nevertheless, the 3 originally infected countries have agreed to establish a militarized quarantine zone along their common borders; see ProMED archive 20140801.2652930. - Mod.JW].

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[2] USA: no need to panic
Date: 2 Aug 2014
Source: Vox [edited]
http://www.vox.com/2014/8/2/5962555/ebo ... in/5712456


The State Department has brought one of 2 US citizens infected with EVD in West Africa back for treatment. The patient is now being treated in a special isolation unit at Emory University Hospital in Atlanta, according to Reuters. Emory University confirmed that they're treating the patient:

"This special isolation unit was previously developed to treat patients who are exposed to certain serious infectious diseases. It is physically separate from other patient areas and has unique equipment and infrastructure that provide an extraordinarily high level of clinical isolation. Emory University Hospital physicians, nurses and staff are highly trained in the specific and unique protocols and procedures necessary to treat and care for this type of patient. The standard, rigorous infection control procedures used at Emory protect the patient, Emory health care workers, and the general public. As the CDC says, EVD does not pose a significant risk to the U.S. public."

The statement also said that a 2nd patient should arrive sometime during the week of 3 Aug 2014. It's most likely that this patient is a female missionary, the other infected American. Transmission of EVD will be prevented using standard protocols, and health officials say that the 2 pose very little risk to the general public.

Even if there were some terrible, unforeseen accident with one of these patients, EVD wouldn't be likely to spread very far. Firstly, EVD doesn't jump from person to person through the air, but through close contact by touching bodily fluids such as sweat, vomit, or blood. The outbreak in West Africa is so severe for a number of key reasons, including a lack of resources, inadequate infection-control measures, and mistrust of health workers [and government]. The USA, by contrast, has far better public-health infrastructure, and that makes all the difference.

For a step-by-step walkthrough of the "EVD loose in America" scenario, read "What would happen if Ebola came to the United States?"
http://www.vox.com/2014/7/30/5948995/wh ... in/5712456.

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[There is an impressive video of the 1st patient in full PPE being assisted by one person to walk into the hospital:
http://www.wsbtv.com/videos/news/raw-vi ... ory/vCmJq7.

See also for the UK:
http://www.itv.com/news/2014-07-31/what ... s-answered.

The same reassuring facts apply to Australia, Canada, other west European countries, and many other developed countries. - Mod.JW]

******
[3] Other news

Militarized borders
------------
1 Aug 2014: A taxi driver in the frontier town of Nzerekore [Guinea], said he had to continue plying his trade across the border to earn an income. "The way I see it, either I die of starvation, or I die of Ebola. I won't take any passengers that have the symptoms, but in most cases it's malaria," whose early symptoms mimic those of EVD and kills thousands each year.
http://www.theguardian.com/society/2014 ... tion-chief

Repercussions elsewhere
-----------------------
1 Aug 2014: Four women have been arrested for illegally selling bush meat in Yamoussoukro, Cote d'Ivoire's capital. The outbreak has had unexpected effects beyond its borders. A military spokesperson for the African Union said it had cancelled a Sierra Leonean battalion rotation to Somalia, where the organisation is battling Al-Shabab Islamists.
http://www.theguardian.com/society/2014 ... tion-chief.

Sierra Leone athletes in UK for Games
-----------------------
1 Aug 2014: On Friday [1 Aug 2014] it emerged that athletes from the country were considering extending their stay amid fears over the Ebola virus disease [EVD] outbreak in West Africa; 2 Sierra Leone athletes at the Games have been tested and cleared for EVD. On the issue of the team returning to Sierra Leone, Unisa Deen Kargbo said: "Athletes have come to me and said they don't want to return because of the EVD situation. There have been discussions back home to see what the final decision will be on that. I have a mandate to return the athletes on 5 Aug [2014], and that's what I'm working towards now" http://www.bbc.co.uk/news/uk-scotland-28621318.

[There is an obvious need for education about avoiding EVD infection for Sierra Leoneans, even for those outside their country. - Mod.JW]

India: airport screening
--------------------
1 Aug 2014: Indian troops deployed in the UN peacekeeping operations in west and central Africa have been put on high alert against the Ebola virus disease [EVD] following the deadliest outbreak of the disease in the region, the Union health ministry said on Friday [1 Aug 2014]. All airports have also been put on alert. Doctors attached to the Netaji Subhash Chandra Bose International Airport in Kolkata [Calcutta] told HT that they would start screening all passengers for EVD from the coming week. As of now, passengers are being tested for Japanese encephalitis and dengue http://www.hindustantimes.com/india-new ... 47485.aspx.

Ethiopia, Kenya Boost Anti-Ebola Measures
------------------------------
3 Aug 2014: Kenya and Ethiopia, home to 2 of Africa's largest transport hubs, said Thursday [31 Jul 2014] they had boosted measures to combat possible Ebola virus disease cases arriving in their countries. Kenya's National Disaster Operation Centre said in a statement that "port health services are on standby, with enhanced screening at border points to prevent and contain any possible disease threat."

Meanwhile, Ethiopia Airlines said it was taking "extraordinary precautions in connection with the outbreak of the disease." Ethiopia's national carrier is a major airline connecting countries across Africa, as well as flying to the Americas, Europe, Asia and the Middle East. "Stringent and specific surveillance is being carried out regarding all flights from West Africa at Addis Ababa airport," the airline said in a statement http://www.tadias.com/08/03/2014/ethiop ... a-measures.

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[4] WHO Case definition recommendations for EVD
Date: 9 Apr 2014
Source: WHO [edited]
http://who.int/csr/resources/publicatio ... act-en.pdf


Case definition recommendations for Ebola or Marburg Virus Diseases
-------------------------------------------
Note: During an Ebola or Marburg outbreak, surveillance should use the case definitions described in section 2, 3 and 4.

2. Community-based surveillance: standard case definition
This definition of "alert cases" for Ebola or Marburg virus disease has been developed for use by the community or community-based volunteers. It may be used for community-based surveillance during the pre-epidemic phase and during the outbreak.

Alert case:
Illness with onset of fever and no response to treatment of usual causes of fever in the area,
OR at least one of the following signs: bleeding, bloody diarrhoea, bleeding into urine
OR any sudden death
Instructions:
If an alert case (living or dead) is identified:
Report the case to a surveillance team or to the closest health centre.

3. During an Ebola or Marburg outbreak, case definitions used by the surveillance:
Important: during an outbreak, the case definitions are likely to be modified to be adapted to new clinical presentation(s) or different modes of transmission related to the local event.

3a. Case definition to be used by mobile teams or health stations and health centres:
SUSPECTED CASE:
Any person, alive or dead, suffering or having suffered from a sudden onset of high fever and having had contact with:
- a suspected, probable or confirmed Ebola or Marburg case;
- a dead or sick animal (for Ebola)
- a mine (for Marburg) [as for gold or diamonds]
OR: any person with sudden onset of high fever and at least 3 of the following symptoms:
- headaches
- vomiting
- anorexia/loss of appetite
- diarrhea
- lethargy
- stomach pain
- aching muscles or joints
- difficulty swallowing
- breathing difficulties
- hiccup
OR: any person with inexplicable bleeding
OR: any sudden, inexplicable death.
Instructions when a suspected case has been identified:
- Report the case to the surveillance team.
- After obtaining express consent, collect a sample.
- Fill in a case notification form.
- Draw up a list of contacts of the suspected case.
If the subject is alive, explain to the patient and his/her family the need to go to hospital to receive adequate medical care. After having obtained the consent of the patient or his/her family, arrange for transfer. If the subject has passed away, explain to the family the need for conducting a safe burial. After obtaining consent, coordinate funeral arrangements with the burial team.

3b. Case definition for exclusive use by hospitals and surveillance teams
PROBABLE CASE:
Any suspected case evaluated by a clinician
OR: Any deceased suspected case (where it has not been possible to collect specimens for laboratory confirmation) having an epidemiological link with a confirmed case
Note: if laboratory specimens are collected in due time during the illness, the preceding categories are reclassified as "laboratory confirmed" cases and "non-case."
LABORATORY CONFIRMED CASE: Any suspected or probable cases with a positive laboratory result. Laboratory confirmed cases must test positive for the virus antigen, either by detection of virus RNA by reverse transcriptase-polymerase chain reaction (RT-PCR), or by detection of IgM antibodies directed against Marburg or Ebola.

NON-CASE: Any suspected or probable case with a negative laboratory result. "Non-case" showed no specific antibodies, RNA or specific detectable antigens.

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[I do not expect soldiers to be happy about being posted into the hot zone at the border; expect some resistance or desertion.

There is, unfortunately, a lot of unreasonable fear in the USA about EVD in the wake of the repatriation of an American case. Apparently, Sierra Leoneans abroad are not the only ones that need educating about EVD transmission and prevention. - Mod.JW

A HealthMap/ProMED-mail map can be accessed at: http://healthmap.org/promed/p/6075.]
Birgitt
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Ebola-Fieber in Westafrika

Beitrag von Birgitt »

Die Ebola-Epidemie in Westafrika hat jetzt auch Nigeria erreicht. Ein Arzt, der einen kürzlich in Lagos an der Krankheit verstorbenen Liberianer behandelt hatte, sei mit dem Virus infiziert, teilte Gesundheitsminister Onyebuchi Chukwu am Montag mit. Zwei weitere Menschen, die in Kontakt mit dem Mann waren und auf Isolierstationen lägen, zeigten ebenfalls Symptome. Insgesamt befänden sich acht Nigerianer in Quarantäne, mehr als 60 weitere würden überwacht [...] Die Bundeswehr trifft mittlerweile Vorkehrungen, um ihre Soldaten in Mali zu schützen.
Ebola hat Nigeria erreicht
04.08.2014 - FAZ
Liberia's government has ordered that all bodies of people killed by the Ebola virus must be cremated. The decision follows the refusal of some communities to allow the burial of Ebola victims on their land. Meanwhile, Nigeria says it has a second Ebola case - that of one of the doctors who treated a man who died from Ebola after his arrival from Liberia. This year's outbreak, the worst ever, has centred on Guinea, Liberia and Sierra Leone, killing 826 people.
Liberia orders Ebola victims' bodies to be cremated
04.08.2014 - BBC

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Ebola-Fieber in Nigeria

Beitrag von Birgitt »

EBOLA VIRUS DISEASE - WEST AFRICA (113): NIGERIA, SECOND CASE
*************************************************************
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Date: Mon 4 Aug 2014
Source: ABC News, Associated Press (AP) report [edited]
http://abcnews.go.com/Health/wireStory/ ... s-24830289
[The URL is very misleading. - Mod.JW]


Nigeria confirms doctor as 2nd Ebola [virus disease] case
---------------------------------------------------------
Nigerian authorities on Monday [4 Aug 2014] confirmed a 2nd case of Ebola virus disease [EVD] in Africa's most populous country, an alarming setback as officials across the region battle to stop the spread of a disease that has killed more than 700 people [more than 800 as of 31 Jul 2014 (WHO) -- see ProMED archive 20140803.2656749, and many more will have died in the last 2 days. - Mod.JW]

Nigerian Health Minister Onyebuchi Chukwu also said test samples were pending for 3 other people who had shown symptoms of EVD.

The confirmed 2nd case is a doctor who had helped treat [PS], the Liberian-American man who died 25 Jul 2014 days after arriving in Nigeria amid the unprecedented outbreak in West Africa. "3 others who participated in that treatment who are currently symptomatic have had their samples taken and hopefully by the end of today [4 Aug 2014] we should have the results of their own tests," Chukwu said.

The emergence of a 2nd case raises serious concerns about the infection control practices that were used while [PS] was in Nigeria, and also raise the specter that more cases could emerge. It can take up to 21 days after exposure to the virus for symptoms to appear. They include fever, sore throat, muscle pains and headaches. Often nausea, vomiting and diarrhea follow, along with bleeding.

[PS], who was traveling to Nigeria on business, became ill while aboard a flight [from Liberia] and Nigerian authorities immediately took him into isolation. They did not quarantine his fellow passengers, and have insisted that the risk of additional cases was minimal. Nigeria is the 4th country to report EVD cases and at least [800] other people have died in Guinea, Sierra Leone, and Liberia.

Nigerian authorities said a total of 70 people are under surveillance and that they hoped to have 8 people in quarantine by the end of Monday [4 Aug 2014] in an isolation ward in Lagos.

[Byline: Bashir Adigun]

--
Communicated by:
ProMED-mail Rapporteur Mary Marshall

[Now the fat is really in the fire. Lagos is Africa's biggest city, with 21 million people, and one of the world's most crowded, with poor healthcare infrastructure.

A businessman relative informs me that he has seen many Nigerian market women at Beijing airport who spend their lives flying from Lagos via Abu Dhabi to buy cheap goods in China and take them back home to sell. Enterprising Nigerian traders travel to every world market.
- Mod.JW

A HealthMap/ProMED-mail map can be accessed at: http://healthmap.org/promed/p/62.]
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Ebola breitet sich in Westafrika aus

Beitrag von Birgitt »

In Nigeria gibt es nach Angaben der Weltgesundheitsorganisation (WHO) inzwischen mehrere Ebola-Fälle. Bei drei Patienten sei es "wahrscheinlich", dass sie mit dem Virus infiziert seien, dazu komme ein Verdachtsfall. Der nigerianische Gesundheitsminister Onyebuchi Chukwu bestätigte einen neuen Fall: Ein Arzt sei mit dem Virus infiziert. Der Mediziner habe sich bei einem Ebola-Patienten angesteckt, der mit dem Flugzeug aus Liberia nach Lagos eingereist und Ende Juli gestorben war. Zwei weitere Menschen, die in Kontakt mit dem Arzt waren, zeigen dem Minister zufolge ebenfalls Symptome - sie liegen nun auf einer Isolierstation [...] Nach neuen Angaben der WHO sind inzwischen in Westafrika mindestens 887 Menschenleben an Ebola gestorben. Die Zahl registrierter Infektionen stieg auf 1603. Die Zahlen der WHO zeigen auch, dass sich die Epidemie innerhalb weniger Tage rasant ausgebreitetet hat: Seit dem 31. Juli kamen 158 neue Todesfälle dazu.
Mehrere Ebola-Fälle in Nigeria
04.08.2014 - tagesschau

Gruß
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Ebola in Westafrika

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EBOLA VIRUS DISEASE - WEST AFRICA (114): USA (NEW YORK CITY), SUSPECTED, MORE
*****************************************************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org

In this update:
[1] USA, NY city suspected
[2] International Response
[3] Superior Health Council recommendations
[4] CDC: Airborne transmission concern
[5] Other EVD news


******
[1] USA, NY city suspected
Date: 4 Aug 2014
Source: CNN [edited]
http://www.cnn.com/2014/08/04/health/eb ... index.html


[A] patient at Mount Sinai Hospital in New York City was being tested after being admitted to the facility with a high fever and gastrointestinal symptoms, according to a statement from the hospital on Monday [4 Aug 2014]. He had recently traveled to a country in West Africa where Ebola virus disease [EVD] has been reported. The patient was placed in strict isolation, and doctors are working to determine the cause of his symptoms.

"(The) likelihood is pretty low" the patient has EVD, said CNN's Dr. Sanjay Gupta. About half a dozen people have recently returned from West Africa and gotten tested because of symptoms consistent with the disease. None of those cases has been confirmed as Ebola, Gupta said.

[Byline: Faith Karimi]

--
Communicated by:
ProMED-mail Rapporteur Mary Marshall

******
[2] International Response
Date: 1 Aug 2014
Source: Washington Post [abridged, edited]
http://www.washingtonpost.com/opinions/ ... story.html


For the past 2 months, the nongovernmental organizations providing the primary response to the Ebola virus disease [EVD] outbreak have realized that the response from regional governments and international public agencies was inadequate. Their call for additional resources, including personnel and supplies, went unaddressed. Now, ending this outbreak will require a much more extensive public health response than has been needed in the past.

In addition, some people are hiding potential cases because they fear that their loved ones will be moved to a clinic or a hospital and placed in isolation, where they will die alone. These concerns are fueled by a lack of education about how the ebolavirus is spread and the difficulty in treating it. People see that their loved ones are alive when they are taken away but are returned in body bags.

Since the 1st EVD cases were reported in March [2014] from forested areas in southeastern Guinea, the outbreak has grown steadily in terms of people infected and geography covered. The virus has infected more than 1300 people; more than 700 have died [latest WHO figures, certainly an undercount, as of 31 Jul 2014, are 1440 including 826 deaths; see ProMED archive 20140803.2656749, and many more will have died in the last 2 days. - Mod.JW]. This is nowhere near the tolls of other infectious diseases, such as HIV/AIDS, malaria, diarrheal disease and tuberculosis, which occur every day in this same region. But the ebolavirus strikes a chord of fear unlike other infectious diseases because of the quick, horrible deaths it causes [and the appallingly high case fatality rate, currently at least 57 percent. - Mod.JW].

The front-line providers of medical care for this outbreak have been dedicated and heroic, but there just aren't enough of them. Doctors Without Borders [MSF] is the primary treatment and community-intervention organization in the 3 [most] affected countries, in addition to the International Federation of Red Cross and Red Crescent Societies, public health agencies organized under the World Health Organization (WHO), and in-country health-care providers and community educators.

These groups know how to fight this disease -- they helped develop the interventions that stopped EVD outbreaks in the past -- but the nongovernmental organizations are "dangerously close to being completely tapped out," a Doctors Without Borders spokesman told me this past week. "It will be impossible to implement an effective control strategy for this outbreak due to a severe shortage of medical professionals on the ground and the geographic spread of the disease."

The U.S. Centers for Disease Control and Prevention announced Thursday [31 Jul 2014] that it will send 50 additional specialists to West Africa to help combat the outbreak, supplementing the 12 CDC professionals already there. For an outbreak involving 3 countries with about 22 million people and 165 000 square miles, that's hardly enough boots on the ground. But the CDC is just one piece of the international response; the WHO and other G-7 nations need to act, too. The WHO does not have the resources to stop this outbreak alone. With a deep respect for the sovereignty of the affected countries, the G-7 nations -- the USA, Canada, Germany, Britain, France, Italy and Japan -- must immediately mobilize and deploy hundreds of infectious-disease experts, along with medical and technical assets to map the epidemic. Hundreds more personnel will be needed to establish treatment centers and to work with local leaders and educators to help people learn how to stop virus transmission.

In addition to these outside resources, the affected countries must step up their commitment to stopping the outbreak. This past week [last week of July 2014], Ernest Bai Koroma, president of Sierra Leone, declared an EVD-related public emergency. He called on the army to quarantine EVD-stricken neighborhoods and to help conduct house-to-house searches for people who may have been exposed to the virus. Such moves acknowledge that this outbreak will not be stopped using the approaches that have worked before. But it is unclear how these efforts are being coordinated with the WHO and NGOs in Sierra Leone. And since this is a regional problem that requires every involved country to halt virus transmission, regional governmental coordination is crucial.

What happens if the response to and management of this outbreak don't shift? The fear and panic are growing each day, with new areas reporting cases and more health-care workers dying. If it continues, West Africa could become politically and economically destabilized. Already, crops are not being harvested because of unrest surrounding the outbreak. Schools in Liberia have closed, and the Peace Corps has removed 340 volunteers from the affected countries. Borders are being closed, too, which can have political and economic impacts.

This coming week's U.S.-Africa Leaders Summit in Washington [DC, 2-4 Aug 2014] must put the EVD crisis front and center. ... Other African countries must also pledge quick and effective responses if cases occur within their borders. We are at a critical point, and the response by the international community and the affected countries will determine whether this outbreak is just a chapter in the region's story or a dramatic and dangerous shift in West Africa's future.

--
Communicated by:
ProMED-mail Rapporteur Mary Marshall

******
[3] Superior Health Council recommendations
Date 4 Jul 2014
Source: Health Belgium [edited]
http://www.health.belgium.be/internet2P ... 511_fr.pdf


Publication of the Superior Health Council No. 9188 [Viral Hemorrhagic Fevers]: Practical recommendations to the attention of healthcare professionals and health authorities regarding the identification of and care delivered to suspected or confirmed carriers of highly contagious viruses (of the Ebola or Marburg type) in the context of an epidemic outbreak in West Africa.

[Congratulations to Belgium for having published this 52-page manual in English and French a month ago. - Mod.JW]

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******
[4] CDC: Airborne transmission concern
Date: 4 Aug 2014
Source: Prison Planet [edited]
http://www.prisonplanet.com/cdc-concern ... virus.html


Despite repeated assurances that the ebolavirus cannot be transmitted via airborne particles, the CDC is concerned about that very outcome and has directed airline staff to take steps to prevent the spread of "infectious material through the air."

While Ebola is highly contagious, the risk of a full blown pandemic has been downplayed by health authorities because, according to our current understanding of the virus, Ebola "is not airborne and is transmitted through contact with bodily fluids, including sweat and blood."

However, with concerns rising that the current strain of the virus, which is the worst in history and has killed 887 people, could in fact be airborne, the Centers For Disease Control has implemented steps to prevent its spread via international air travel.

A CDC advisory entitled Interim Guidance about Ebola Virus Infection for Airline Flight Crews, Cleaning Personnel, and Cargo Personnel reveals that the federal agency is concerned about airborne contamination.

The advisory urges airline staff to provide surgical masks to potential Ebola victims in order "to reduce the number of droplets expelled into the air by talking, sneezing, or coughing."

The CDC is also directing airline cleaning personnel to "not use compressed air, which might spread infectious material through the air."

[Byline: Paul Joseph Watson]

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[This is out of an abundance of caution. There is no evidence that airborne transmission has ever occurred naturally between humans -- nor between animals, nor between animals and humans -- in the open air as opposed to in the lab. Aircraft air is filtered. If ebolaviruses were commonly transmitted through the air, a much larger number of people, especially in the crowded capital cities, would have shown symptoms by now, as during a typical flu epidemic. - Mod.JW]

[US CDC and other health authorities have advised and continue to advise standard, contact, and droplet precautions for patients with Ebola virus disease. The use of a surgical mask is to reduce transmission of droplets and does not prevent "airborne" transmission such as that observed with measles. Of course in an airplane, a certain amount of improvisation is required to implement infection control measures. The CDC guidance can be found at:
http://www.cdc.gov/quarantine/air/manag ... lines.html
- Mod.LM]

******
[5] Other EVD news

A passenger died in the UK after arriving from Freetown, Sierra Leone [EVD negative]
-------------------------------------
The woman, said to be 72, became ill on the gangway [at Gatwick airport, England] after she left a Gambia Bird jet with 128 passengers on board. She died in hospital on Saturday [2 Aug 2014]. The plane was quarantined as officials desperately tried to trace everyone who had been in contact with the woman.

[A] shocked staff member said: "The woman was sweating buckets and vomiting. Paramedics arrived to try and help her. The next thing, everybody was there. ... emergency crews, airfield operations, even immigration. They closed down the jet bridge and put the aircraft into quarantine. They took everyone's details, even the guy who fuels the aircraft. It stopped at Banjul in The Gambia before landing in Gatwick at 8:15 am on Saturday [2 Aug 2014] after a 5-hour flight. Public Health England said the woman showed no symptoms during the flight. The patient was not symptomatic on the plane, and, therefore, there is no risk of EVD being passed on to either flight crew or other passengers. England has world class health care and disease control systems which are active permanently, regularly tested, and proven to be effective. If the UK does see a case of imported EVD, this will not result in an outbreak in this country."

South East Ambulance Service Communications chief Janine Compton said: "We attended Gatwick airport at 8:30 am on Saturday [2 Aug 2014] to attend an adult female patient who was seriously ill. She was taken to East Surrey Hospital in Redhill where she subsequently died."

At around 11:00 pm on Sunday [3 Aug 2014], the Department of Health said that tests for the deadly ebolavirus on the woman who died at Gatwick had proved negative http://www.mirror.co.uk/news/uk-news/eb ... z39SyiCZNB.

[Public Health England is to be congratulated on their comprehensive response to this emergency. - Mod.JW]


Liberia hospital "forced to turn away some EVD cases"
----------------------------
3 Aug 2014: The withdrawal of some international medics from Liberia following the infection of 2 US health workers with the Ebola virus has exacerbated the healthcare crisis caused by the epidemic. The overcrowded and understaffed Elwa hospital in the capital, Monrovia, where the 2 worked, has been forced to turn away some EVD cases.

[So where are they supposed to go now? - Mod.JW]


Liberia: Roadblocks, teargas
------------------
4 Aug 2014: On Sunday morning [3 Aug 2014], as Liberians prepared for church, residents of the St. Paul's Bridge community staged roadblocks in protest of dead bodies lying in their community. "We have an Ebola body on the ground [and] up till now nobody to pick it up. We've been waiting for 4 days now and nobody to pick it up," said Mohamed Kollie, a resident of the area. "We decided to put roadblock down, and the police started shooting tear gas. We have 4 bodies lying down in St. Paul Bridge community alone, one in the Island Clinic area under the tree and the other 3 in houses around here."

Residents are visibly scared as a result of the deadly virus, and people are not reporting their sick to health centers but are instead caring for them at home http://frontpageafricaonline.com/index. ... s-unburied.


Liberia: Burning of bodies starts
--------------------------
4 Aug 2014: The Liberian Government announced Sunday [3 Aug 2014] that it has begun burning the bodies of victims of the deadly ebolavirus. "We have decided to burn the bodies," Information Minister Lewis G. Brown told the New Dawn Sunday. He said the decision to cremate the bodies of EVD victims was reached earlier on Sunday. The government's decision to cremate the bodies of victims of the tropical disease follows the increasing wave of resistance by residents of several communities to allow the burial of EVD victims in their areas. "Cremation will take place in Marshall beginning today [4 Aug 2014]," Mr. Brown said. Marshall is located in Margibi County, another county affected by the tropical disease here.

On Saturday [2 Aug 2014], dozens of residents from several communities protested against the burial of Ebola victims in their areas. The 1st burial site for over 25 bodies in the township of Johnsonville was abandoned by health workers after the land owner refused to sell the land to bury EVD victims http://www.thenewdawnliberia.com/index. ... &Itemid=59.


UK: "Midwives refused to see me."
------------------------------
4 Aug 2014: "I'm now 2/3rds of the way through my 2nd pregnancy and was due to have a routine midwife's appointment the day after my flight landed at Heathrow. The only problem was that my midwives refused to see me. They took this precaution as a result of 2 factors, my poorly toddler, who had a slight temperature, and heavy news coverage of the EVD outbreak in West Africa. They referred me instead to my GP. Their wisdom was debatable. I was travelling from Nigeria, a country in which so far only 2 people have been quarantined as a result of possible contact with the disease [now 8, with a 2nd confirmed case - Mod.JW]. And in any case, a GP's waiting room is not the best place to take a potentially deadly virus. Thank goodness I'm not infected."

[EVD education is obviously needed, not only in West Africa but also among UK's National Health Service staff. - Mod.JW]


Ebola Serum: Explaining Experimental Treatments
-----------------------
2 Aug 2014: An American doctor working in West Africa and another health care worker, also American, who contracted EVD there have both received experimental treatments for the deadly viral disease, according to news reports. Nancy Writebol, a worker with the charity Samaritan's Purse, received an experimental serum, and Dr. Kent Brantly, from the same charity, received a blood transfusion from a patient who recovered from Ebola, according to NBC News. Both of the health care workers are also being flown to an isolation unit in an American hospital for treatment, according to news reports [one has already arrived; see ProMED archive 20140802.2655022. - Mod.JW]. Though there are conflicting reports, and no one is saying exactly what the experimental serum is, its likely that both of the reported methods contained antibodies to the ebolavirus, said Dr. William Schaffner, a professor of preventive medicine and infectious diseases at Vanderbilt University Medical Center in Nashville, Tennessee. Delivering antibodies to a patient could slow the virus's replication and give the immune system time to recover http://news.yahoo.com/ebola-serum-expla ... 03260.html.


Emirates airline halts flights to Guinea
------------------------------
Emirates has become the 1st major airline to halt flights to Guinea, in the west African region affected by the recent EVD outbreak. Upon announcing the stoppage of service, the airline said: "The safety of our passengers and crew is of the highest priority and will not be compromised" http://flightclub.jalopnik.com/airlines ... 51/+travis.


Lagos Government Warns Church Not To Accept EVD Victims
--------------------------------------------------
3 Aug 2014: Officials of Lagos State Ministry of Health and the Federal Government visited the General Overseer of the Synagogue Church of All Nations (SCOAN), Prophet Temitope Joshua, seeking his cooperation in ensuring Ebola victims are not brought to his church for healing http://saharareporters.com/2014/08/03/l ... gue-church and http://en.starafrica.com/news/liberia-s ... ebola.html.

[The church has an international congregation. - Mod.JW]


Liberia shuts land borders with neighbours over EVD
---------------------------------------------
3 Aug 2014: As a means of containing further spread of the disease, President Johnson-Sirleaf ordered the closure of the country's 3 land borders, sources said. Liberia has land borders with Sierra Leone, Liberia and Cote d'Ivoire.

[Although WHO has not yet recommended any trade or travel restrictions, countries have started taking matters into their own hands. But besides major road crossings, as in other continents, African countries have many uncontrolled cross-border footpaths along which people and goods move daily. - Mod.JW]


Russian experts arrive in West Africa
------------------------
3 Aug 2014: Specialists from Russia's Health Ministry have arrived in Africa to join the fight against the EVD outbreak in the region, a spokesman for the ministry said Sunday [3 Aug 2014]. "Russian specialists have been tasked with providing the research and methodology aid to their local counterparts as well as with conducting an epidemiological analysis of the situation and developing recommendations to ensure infectious security," Oleg Salagai said http://en.ria.ru/russia/20140803/191668 ... Fight.html.

[The Russian embassy in Guinea has been placed in strict quarantine. - Mod.JW]

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Götz Krieger
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Re: Ebola - Guinea, Liberia, Sierra Leone und Nigeria

Beitrag von Götz Krieger »

Riskantes Experiment: Serum gegen Ebola könnte US-Patienten gerettet haben

Der Arzt Kent Brantly und die Missionarin Nancy Writebol aus den USA sind die ersten Menschen, an denen jemals ein Serum gegen Ebola getestet wurde. Möglicherweise hat ihnen das experimentelle Mittel das Leben gerettet.

Grassiert eine Seuche, lassen ethische Dilemmas selten auf sich warten. Häufig brechen Epidemien in jenen Ländern der Welt aus, in denen es um die Infrastruktur der Gesundheitsversorgung schlecht bestellt ist und in denen es an Geld mangelt, um Erkrankte mit den besten zur Verfügung stehenden Mitteln zu behandeln.

Aids beispielsweise tötet jährlich südlich der Sahara insgesamt etwa eine Million Menschen, während in Europa durchschnittlich weniger als zehntausend daran sterben. Das Dilemma, das sich jetzt nach dem Ausbruch der Ebola-Epidemie in Westafrika offenbart, ist ein ähnliches: Welcher Patient bekommt ein Medikament, das sich im Tierversuch als erfolgreiches Mittel im Kampf gegen die tödliche Infektion erwiesen hat?...
http://www.spiegel.de/gesundheit/diagno ... 84474.html

Gruß
Götz
Birgitt
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Ebola - Guinea, Liberia, Sierra Leone, Nigeria, Marokko

Beitrag von Birgitt »

EBOLA VIRUS DISEASE - WEST AFRICA (115): MOROCCO SUSPECTED, NIGERIA APPEAL, WHO
*******************************************************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org

In this posting:
[1] Morocco suspected ex Liberia
[2] Nigeria: call for clinicians
[3] WHO update


******
[1] Morocco suspected ex Liberia
Date: Mon 4 Aug 2014
Source: CIDRAP (Center for Infectious Disease Research & Policy) News [summ., edited]
http://www.cidrap.umn.edu/news-perspect ... ak-spreads


[excerpts]

Travel cases, disease spread in Morocco
---------------------------------------
[T]he scope of the [Ebola virus disease] outbreak continued to expand, with the detection of a travel-linked case in Morocco. [According to a 1 Aug 2014 AllAfrica report, Morocco's Minister of Internal Affairs, Mr Morris Dukuly] on 30 Jul 2014 said a Liberian citizen has died from EVD in Morocco. The patient had left Liberia 2 days before he died. The report did not include any details about the man's flight or contact tracing of airline passengers, airline staff, or health workers who may have had contact with the man. [Neither are there any details of which lab made the confirmation. - Mod.JW]

[Byline: Lisa Schnirring]

--
Communicated by:
ProMED-mail Rapporteur Mary Marshall

[Royal Air Maroc has extensive routes from Morocco to Africa, Europe, and the Middle East, and also flies to New York and Montreal [Canada]; see:
http://airinfodotorg.files.wordpress.co ... -14-08.png. - Mod.JW]

******
[2] Nigeria: call for clinicians
Date: Tue 5 Aug 2014
From: Patrick M Nguku <drnguku@gmail.com> [edited]
Via Nigerian biomedical and life scientists yahoo group


This is URGENT
--------------
Graduates and residents NFELTP [Nigeria Field Epidemiology & Lab Training Program:
As you all know we have 2 confirmed cases of Ebola virus disease and a few suspect/probable cases under investigation. The FELTP has been substantially involved in supporting epidemiology work (contact tracing, surveillance, training, etc) since 23 Jul 2014.

Adequate and complete contact tracing and immediate isolation of cases is the only way to interrupt transmission. We need to support the response with clinicians who can support case management.

If you are a clinician and you are willing to support the case management team please give me a call on 07034119819 or Chinyere on 08188123311 as soon as possible.

If you know a clinician willing to help give us a call too. PPE, adequate training and other supportive requirements will be provided for any clinicians willing to support case management. This is urgent.

--
Patrick M Nguku
<drnguku@gmail.com>

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Communicated by
ProMED-mail
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[Let us hope many clinicians answer this call, from both Nigeria and abroad. - Mod.JW]

*******
[3] WHO update
Date: Mon 4 Aug 2014
Source: WHO Global Alert and Response (GAR), Disease Outbreak News [summ., edited]
http://www.who.int/csr/don/2014_08_04_ebola/en/


Ebola virus disease update -- West Africa
-----------------------------------------
As of 1 Aug 2014, the cumulative number of cases attributed to EVD in the 4 countries stands at 1603 including 887 deaths.

The distribution and classification of the cases are as follows:
- Guinea, 485 cases (340 confirmed, 133 probable, and 12 suspected) including 358 deaths;
- Liberia, 468 cases (129 confirmed, 234 probable, and 105 suspected) including 255 deaths;
- Nigeria, 4 cases (0 confirmed, 3 probable, 1 suspected) including 1 death;
- Sierra Leone, 646 cases (540 confirmed, 46 probable, and 60 suspected) including 273 deaths.

Between 31 Jul-1 Aug 2014, 163 new cases (laboratory-confirmed, probable, and suspect cases) of EVD [including] 61 deaths were reported from the 4 countries as follows:
- Guinea, 13 new cases [including] 12 deaths;
- Liberia, 77 new cases [including] 28 deaths;
- Sierra Leone, 72 new cases [including] 21 deaths;
- Nigeria, 2 new probable cases -- one is a health-care worker and one is a Nigerian who travelled to Guinea -- and a suspected case in a nurse.

Human and financial resource mobilization continues to be sought from WHO's partners, UN agencies, and other stakeholders. On Friday [1 Aug 2014], WHO and the affected countries issued the Ebola Virus Disease Outbreak Response Plan in West Africa covering Guinea, Liberia, Sierra Leone, neighbouring states, and other countries in the region from July-December 2014 (http://who.int/csr/disease/ebola/outbre ... se-plan/en).

The joint WHO-tri-national plan, estimated at USD 100.5 million (funding gap is USD 71 million) calls for additional human and material resources that align with the measures in the Joint Declaration.

Disease update
--------------
[A table showing confirmed, probable, and suspect cases and deaths from Ebola virus disease in Guinea, Liberia, Nigeria, and Sierra Leone is available at the source URL above.]

The total number of cases is subject to change due to reclassification, retrospective investigation, consolidation of cases and laboratory data, and enhanced surveillance. Data reported in the Disease Outbreak News are based on best available information reported by Ministries of Health.

* Note to the media: On 31 Jul 2014, a Disease Outbreak News (DON) was posted to the WHO corporate website reporting EVD figures for the period covering 24-27 Jul 2014. On the same date, a DON was posted to the website for the WHO Regional Office of Africa reporting EVD figures for the period covering 28-30 Jul 2014. Today's [4 Aug 2014] DON reflects data for the period covering 31 Jul-1 Aug 2014.

--
Communicated by:
ProMED-mail Rapporteur Marianne Hopp

[163 new cases in 24 hours -- the disaster is accelerating -- or maybe it's just the case finding and epidemiological surveillance that are getting better.

More volunteers are urgently needed in the field, not only in Nigeria. - Mod.JW

A HealthMap/ProMED-mail map can be accessed at: http://healthmap.org/promed/p/41.]
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Ebola - Auswärtiges Amt reagiert auf Epidemie

Beitrag von Birgitt »

Das Auswärtige Amt rät wegen der Ebola-Epidemie in Westafrika "dringend" von Reisen nach Sierra Leone, Liberia und Guinea ab. Außerdem sei es nicht auszuschließen, dass Ausreisemöglichkeiten aus diesen Ländern weiter beschränkt würden, heißt es in den aktualisierten Reise- und Sicherheitshinweisen für die drei Länder. Trotz internationaler Bemühungen sei ein Ende der Ausbreitung nicht absehbar. Die Fluglinie British Airways setzte wegen der Ansteckungsgefahr ihre Flüge von und nach Liberia sowie Sierra Leone bis Ende des Monats aus.
Reisewarnung für Ebola-Länder
05.08.2014 - tagesschau

Gruß
Birgitt
Alexander
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Re: Ebola - Guinea, Liberia, Sierra Leone, Nigeria, Marokko

Beitrag von Alexander »

Ebola: Der Plan für den Fall der Fälle

Die Ebola-Epidemie in Westafrika ist außer Kontrolle. Mehr als 1.600 Fälle sind gemeldet, fast 900 Menschen sind daran gestorben. Wie groß ist die Gefahr, dass Infizierte über den Frankfurter Flughafen nach Deutschland kommen? Und welche Vorsichtsmaßnahmen gibt es? mehr...

Grüsse
Alexander
The one who follows the crowd will usually go no further than the crowd. Those who walk alone are likely to find themselves in places no one has ever been before.

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Ebola in Westafrika

Beitrag von Birgitt »

EBOLA VIRUS DISEASE - WEST AFRICA (116): MOROCCO NOT, NIGERIA, BUSHMEAT, MORE
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A ProMED-mail post
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International Society for Infectious Diseases
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In this update:
[1] Morocco [NOT], Philippines & Brazil suspected
[2] Nigeria
[3] Bushmeat in the UK
[4] Guinea: bushmeat, FAO
[5] Europe: risk
[6] Other EVD news


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[1] Morocco [NOT], Philippines & Brazil suspected
Date: Sun 3 Aug 2014
Source: Before Its News [edited]
http://beforeitsnews.com/alternative/20 ... 05636.html


The Phillipines has reported the country's 1st suspected cases of the ebolavirus. According to the country's health officials, 7 workers who returned to the Philippines from Sierra Leone are showing symptoms similar to those of the tropical virus.

The Minister of Internal Affairs, Mr. Morris Dukuly, has disclosed that a Liberian has died of the deadly Ebola virus in Morocco [He tested negative; it was a heart attack, see in French: http://www.aufaitmaroc.com/maroc/societ ... -Du2Gd02Cg, courtesy of ProMED subscriber Giuseppe Michieli. - Mod.JW]

A man who landed at Guarulhos airport in Sao Paulo, Brazil in the morning, was taken to the Emilio Ribas hospital, and is hospitalized in an isolated area. The African, whose name was not revealed, is undergoing tests that may reveal ebolavirus contamination [There is no information on the country of origin nor on the Brazilian lab doing the testing and no report in the mainstream media. It is difficult to know which of the many rumours of cases floating around the internet to post, knowing that many will turn out to be false alarms. But ProMED is an early warning service. - Mod.JW].

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[2] Nigeria
Date: 5 Aug 2014
Source: Channels TV [excerpted, edited]
http://www.channelstv.com/2014/08/05/eb ... sadvantage


The Minister of Health, Professor Onyebuchi Chukwu, has reiterated the government's determination to put an end to the spread of Ebola virus disease [EVD] in Nigeria and protect all its citizens from contracting the disease.

While speaking on the Tuesday [5 Aug 2014] edition of Channels Television's Sunrise Daily, he noted that it would be wrong to speculate on whether there had been more cases of the virus but maintained that some health workers who attended to the late PS had shown fever symptoms, but the tests on them turned out negative, with the exception of the female doctor who had been confirmed to have contracted the ebolavirus. On the general situation of things in the country, he said that 70 people, who had primary contacts with the Liberian, were currently under active surveillance, and having shown suggestive symptoms, about 8 people have been quarantined. He added that the family of the female doctor has also been kept under watch and surveillance; they have been tested and none of them had tested positive yet.

Questions were raised about Nigeria's involvement in the conference of African Health Ministers held in Accra, Ghana and how it has allegedly failed to address the issue of Ebola spread across the continent and into Nigeria, and Prof. Chukwu explained that indeed the conference addressed the issues of Ebola spread.

He explained that the spread of EVD was "just unfortunate," as the late PS, who was the index case, travelled to Nigeria against the warnings of his own country. "How he ended up travelling and not disclosing full information to those who were asking (is unknown). Even on the hospital bed, he was still denying. It's just unfortunate that he brought this into Nigeria, but then it tells you that every country of the world is indeed at risk," he said. He, however, gave assurances that the global community was aware of this risk and that there were efforts to address it. "This week, the WHO is meeting in Geneva to review all strategies that are in place and to see if anything more drastic could be suggested."

Besides the use of electronic media to run jingles, which had started in March 2014, the Health Minister disclosed that the scope of communication had been widened with the launch of a new website: http://www.ebolaalert.org, which is an interactive website that accommodates sharing of suggestions, airing complaints and answering questions from citizens. This is in addition to accounts being opened on the social media platforms Facebook and Twitter. A toll-free telephone line: "0800EBOLAHELP" has also been launched for the public, dedicated to reaching the health agencies and help desks set up to attend to citizens.

Border screening was also mentioned as part of the strategies. This includes temperature screening and data collection of all passengers entering the country. He added that there had been a directive for corpses not to be brought into the country without proper death certificates. He insisted that the responsibility was on the families of the dead persons to prove the cause of death, while the corpses would also be subjected to tests by Nigerian authorities.

Many citizens have expressed the view that the doctors' strike was a blessing in disguise for Nigeria, owing to the view that the Liberian carrier of the ebolavirus would have been taken to a public hospital where there are usually more patients, and this would have led to a possibly uncontrollable spread, but Professor Chukwu believes that while this could be a valid opinion, the country still remained at a disadvantage with the doctors being on strike. Although, according to the Minister, the non-availability of doctors in government hospitals across the country hadn't affected the management of EVD yet, he warned that there were possibilities of more cases of the virus springing up in the coming days, and at this point, more experts would be needed to manage it. He appealed to the striking doctors to get back to work, as most of their requests had been addressed by the Federal Government.

Nigerians have also expressed fear that Nigeria lacked the infrastructural capacity in its health sector to handle the outbreak of EVD. The Health Minister, while admitting that there was dire need for the country to move faster in that aspect, said that work had commenced on providing more isolation facilities across the country and within the hospitals to prevent the spread of the virus. He commended the Lagos State Government for providing the required facilities to quarantine and treat patients. "Given the way Lagos State has been proactive in this matter, I want to commend the authorities of Lagos State. I believe still working with them, they will be able to provide additional spaces," he said.

The Minister also promised to do more on sensitizing young Nigerians on EVD. He revealed that the Ministry had commenced work on collaborating with schools across the country to provide proper information to the students.

On the suspected cause of the virus, Prof Chukwu maintained an earlier plea that Nigerians who consider bats as delicacies should avoid their consumption and that of other bushmeat, as they could have been in contact with bats. He, however, added that those processing the bats and other bushmeat were more in danger of contracting the ebolavirus, as they are the ones who handle the animals in their raw state. He explained that the meat, if well heated up, could be free of the ebolavirus.

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[3] Bushmeat in the UK
Date: Sat 2 Aug 2014
Source: Express UK [edited]
http://www.express.co.uk/news/uk/494920 ... rus-hit-UK


The black market demand for monkey meat straight out of Africa could see the deadly ebolavirus hit the UK, experts have warned today [2 Aug 2014]. Eating bush flesh is one of the main ways ebolavirus is transmitted to humans, and 7500 tonnes of illegal meat enter the UK every year. The exotic meats are eaten by some sectors of African immigrants in Britain as a luxury dish, and the trade has been defended on cultural grounds.

A BBC investigation previously discovered the markets at Ridley Road, London sold giant rats among other smuggled meats. It is known as a prime example of an area where black market meats are sold and is replicated all over the country. Dr Yunes Teinaz, a former environmental health official, warned the bushmeat is sold "all over the country" and is a "huge" health risk. This meat is sold everywhere. It's smuggled in vast quantities. "It's supplied all around Britain. It poses a potentially huge risk to public health, yet we are doing nothing to tackle it." The meat is often sold on the black market in the UK to people of African descent and to those who are already familiar with sellers. Speaking to the Daily Mail, one trader said: "Everybody knows where you can get it. Bush meat is like drugs; you can get it everywhere if you know the right people, but you won't see it openly on sale. It's word of mouth and under-the-counter deals."

[Byline: Dion Dassanayake]

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[4] Guinea: bushmeat, FAO
Date: 4 Aug 2014
Source: Guardian UK [edited]
http://www.theguardian.com/global-devel ... fruit-bats


Health workers struggle to separate myth from reality about EVD as residents say abandoning tradition is out of the question.

Medical teams struggling to curb EVD in west Africa have been discouraging bush meat consumption, believed to have caused the outbreak, but some rural communities dependent on the meat for protein are determined to continue their traditional hunting practices. While meat from wild animals such as fruit bats, rodents and forest antelopes has largely disappeared from market stalls in main towns such as Gueckedou in southern Guinea -- the epicentre of the disease -- and the capital Conakry, following campaigns to avoid contamination, it is still being eaten in remote villages despite the risks.

"Life is not easy here in the village. They [authorities and aid groups] want to ban our traditions that we have observed for generations. Animal husbandry is not widespread here because bushmeat is easily available. Banning bushmeat means a new way of life, which is unrealistic," said Saa Fela Leno, who lives in Nongoha village in Gueckedou.

Poor knowledge and superstition especially in rural communities, as well as cross-border movement, a poor public health infrastructure and other epidemiological causes have contributed to its spread. The immediate concern is to halt human-to-human transmission. Discouraging bushmeat consumption and introducing livestock as an alternative to hunting are part of long-term solutions against the risks of contracting EVD from the wild, said Juan Lubroth, chief veterinary officer with the Food and Agriculture Organisation (FAO) in Rome. "We recognise the importance that bushmeat has to quality nutrition that you may not get from only crop-based diets. We do not say that you should stop wild meat ... but can we replace the need to go to the forest and hunt wildlife with having a source of livestock and livelihood that can be safer?" Lubroth said. "Can we have a development agenda where we could have poultry production, sheep, goats, pigs ... so that there is no undue encroachment into the forest for hunting?"

Promoting hygienic practices to avoid contracting EVD is a protracted endeavour. Urging new norms for diet is far harder. Lubroth said: "It becomes very difficult to convey to an individual about a threat that cannot be seen, in this particular case a virus. One of the major aspects is to build trust with communities or villages. The sociology, the anthropology, the communication is so important, not like the veterinary or the wildlife or medical sciences," he told IRIN, explaining that epidemiological facts have to be translated in simple ways for ordinary people to understand, by using local allegories for instance. Yet promoters of health messages, such as Mariame Bayo in Guinea, have been threatened with death in villages where residents strongly oppose aid workers. "In Nongoha, we were told that if we don't leave, we would be cut into pieces and our flesh thrown into the water," she said.

Health minister, Colonel Remy Lamah said: "It is difficult to change a society's way of life, but when it comes to saving lives, I think no effort should be spared. We didn't say that people will no longer eat meat. [Discouraging bush meat] is just an interim measure," he added.

Moustapha Diallo of the International Federation of Red Cross and Red Crescent Societies, however, said fewer villages across the 3 west African countries remained hostile to aid groups, following public education campaigns. "The main behaviour change needed is at funerals, where a lot of cases are being contracted. That and good protective measures at health structures are the most important targets," said Stephane Doyone, west Africa coordinator of Medecins sans Frontieres [MSF].

Exposure to infected people as families care for sick relatives at home, touching bodies during burials or even hospital-acquired infections continue to account for the high death toll. However, rural communities still hunting for bushmeat risk further spillover of the virus from infected wild animals, according to the FAO. "We will die if we must, but abandoning our traditions is out of the question. It is true that we have lost many relatives. That's fate," said Gueckedou resident Mamadi Diawara. Guinea's communication minister, Alhousseine Makanera Kake, said bringing the outbreak under control is fraught with challenges. "Obstacles will remain until the outbreak is over. It goes without saying that we will not overcome this easily," he said.

It is still unclear why the Ebola virus crossed from its animal hosts this time in west Africa while communities have consumed bushmeat for generations without infection. "We do not know enough about EVD's natural cycle in the jungle. I'm sure it ticks away every year or every season, but it only makes it into the news when we have human mortality," said Lubroth. While warning against consuming bats or handling sick or dead animals, Lubroth said an outright ban on bush meat "will likely see it go underground, and that is actually worse. So we talk more about management than prohibition." Providing alternatives to bushmeat may solve only part of the problem. In the long run, better equipped and resourced public health systems remain crucial to curbing outbreaks.

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[5] Europe: risk
Date: 4 Aug 2014
Source: CIDRAP News [edited]
http://www.cidrap.umn.edu/news-perspect ... ak-spreads


The surge of new cases in West Africa and spread of the disease to new areas prompted the European Centre for Disease Prevention and Control (ECDC) to look at the risk again, its 3rd evaluation since the outbreak began in March [2014].

It said that overall, the risk of infection is still low if basic precautions are followed. The ECDC emphasized that EVD required direct contact with blood, secretions, organs, or other body fluids of dead or living infected people or animals. "Unlike influenza, the virus is not transmitted by air or droplets."

Though people infected with EVD may arrived in the EU from outbreak areas, the risk of secondary transmission to direct contacts is still considered very low if infection-prevention measures are followed, the ECDC said. It added that prevention measures can include information for returning travelers and health providers. For tourists, visitors, or residents of countries affected by the outbreak, the risk of infection is still very low if basic precautions are followed, the agency said. Steps include avoiding contact with symptomatic patients or dead bodies and their bodily fluids and avoiding unprotected sexual contact with a patient who has recently recovered from the disease.

***The ECDC emphasized that the highest risk for EU residents and visitors is within the healthcare systems of affected countries.*** [Asterisks added by ProMED].

[Byline: Lisa Schnirring]

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[6] Other EVD news


CDC: "contaminated air" NOT
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5 Aug 2014: ProMED expressed concern about a report that CDC had reversed itself and admitted the possibility of airborne transmission of the ebolavirus responsible for the current epidemic; see ProMED archive 20140804.2659805. A reader (Ryan McGinnis) has pointed out that the source quoted is a notorious conspiracy theory website. It now transpires that it was an unfortunate choice of words in CDC's Ebola hospital Factsheet, referring to aerosols generated by certain medical procedures, NOT airborne transmission as occurs with flu viruses http://investmentwatchblog.com/cdc-remo ... la-webpage.

[CDC has corrected it; see http://www.cdc.gov/vhf/ebola/hcp/infect ... tions.html. ProMED regrets adding to the confusion.]


2nd infected American aid worker with EVD has arrived in the USA
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5 Aug 2014: The 2nd American aid worker infected with EVD in Liberia arrived in the United States on Tuesday [5 Aug 2014] for treatment. NW, 59, will be treated in an isolation unit at Emory University Hospital in Atlanta, the same hospital that is treating the other American, KB. A specially outfitted plane carrying NW landed just outside Atlanta on Tuesday [5 Aug 2014] morning http://www.nbcnews.com/storyline/ebola- ... -s-n172706.


USA: not turning back flights
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5 Aug 2014: Asserting that there was "no significant risk" to the country from the EVD outbreak in West Africa, the White House has ruled out turning back flights coming to the USA and said there are screening measures in place to ward off threats from the disease.

When asked whether flights coming to the USA would be turned back over Ebola [concerns]: "No, not at this point," the White House Press Secretary, Josh Earnest, told reporters. "It's important for the public to understand that the reason that it's important to identify the symptoms is you're not contagious unless you exhibit the symptoms of this disease. That's what differentiates it from a common cold or the flu, where, of course, individuals can be contagious before they start exhibiting the symptoms," he added http://www.firstpost.com/world/ebola-ou ... 50169.html.

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[A ProMED-mail HealthMap of Nigeria can be accessed at http://healthmap.org/promed/p/62.]
Birgitt
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Ebola-Fieber in Westafrika

Beitrag von Birgitt »

Der Ebola-Epidemie sind laut Weltgesundheitsorganisation (WHO) wahrscheinlich bereits mehr als 900 Menschen zum Opfer gefallen. Aus den betroffenen vier Ländern in Westafrika seien bis zum 4. August insgesamt 1711 Fälle von Ebola oder Ebola-Verdacht gemeldet worden. 932 dieser Patienten seien gestorben [...] Die Seuche scheint auch auf Gebiete außerhalb Westafrikas überzugreifen. In Saudi-Arabien starb ein wegen Ebola-Verdachts behandelter Mann. Der 40-Jährige lag in kritischen Zustand auf einer Isolierstation und war auf das gefährliche Virus getestet worden, teilte das Gesundheitsministerium mit. Er starb in einem Krankenhaus in Dschidda. Ob der Mann tatsächlich an Ebola erkrankt war, steht noch nicht fest [...] Saudi-Arabien vergibt keine Visa mehr an Muslime aus Sierra Leone, Liberia und Guinea, die zur Pilgerfahrt nach Mekka wollen. Diese Regelung solle auf alle Länder ausgedehnt werden, in denen das Ebola-Virus aufgetaucht ist [...] Erstmals wird ein Ebola-Patient nach Europa geflogen. Die spanische Regierung lässt einen erkrankten Staatsbürger aus Westafrika in sein Heimatland zurückbringen.
Ebola-Verdacht auch in Saudi-Arabien
06.08.2014 - tagesschau

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Birgitt
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